Scientists at the University of Montreal discovered new properties of the Y chromosome during their research. This discovery will help explain the difference in the course of some diseases in men and women.
Lead author of the study, Professor Christian Deshepper, explained that the new work will help to better understand why genes on the Y chromosome favor the peculiar functioning of cells depending on a person's sex. During the experiment, scientists altered two male hereditary factors, transforming signaling pathways. In conditions of nervous overstrain, this affects the protective functions of the heart cells, saving them from stress.
The study found that male genes regulate differently from the mechanisms used by most other hereditary factors in non-sex chromosomes. Therefore, the direct effect is replaced by an effect on cellular functions and protein production.
Deshepper noted the importance of this discovery. According to the professor, the new study will make it possible to understand why the properties of genes of the Y-chromosome are poorly understood even in the 21st century with advanced technologies used, including in medicine and biology.