HIV drugs can reduce the risk of diabetes. The corresponding conclusions were made by a team of scientists from the University of Virginia School of Medicine.
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As part of the work carried out, specialists noticed that patients who took drugs for HIV and hepatitis B showed less significant risks of facing type 2 diabetes. In some cases, it was about 33%. This effect is due to the mechanism of action of the drug. The conclusions are drawn from experiments on cell samples, as well as a model of diabetes in mice.
The authors of the study turned their attention to IOTN. Data from 128 thousand people with HIV-1 or hepatitis B were analyzed. Observations were continued for 17 years. The effect was achieved by reducing insulin resistance and activating the inflammasome. This multiprotein complex is responsible for the activation of the inflammatory response in the body.