German scientists were able to discover the mechanism of the natural immune defense of the human body against coronavirus infection. The specialists presented the results of their research in the material for the journal Nature Immunology.
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It is reported that within the framework of the study, scientists were able to identify several specific molecular regions at once that are located on the surface of antigen-presenting cells. These cells are recognized by T cells and are directly involved in the formation of the immune response. To this end, scientists conducted a thorough analysis of 180 patients who recovered from COVID-19. In addition, donated blood samples collected even before the coronavirus pandemic began were also studied.
As it turned out, a small number of immune T cells, which are aimed at fighting the coronavirus and are able to recognize the components of COVID-19, are present in the blood of 81% of donors who have not been exposed to the disease. Scientists believe that this may be due to previous contacts of donors with coronaviruses of other types, for example, those that cause colds in humans. However, the authors of the study argue, such a T-cell response is the full equivalent of a full-fledged immune response from a new type of virus.
Moreover, in all people who have had coronavirus, scientists have also identified T cells with a similar set of characteristics and an immune response to COVID-19. Moreover, similar features were found even if the antibody response in the body was not recorded, reports Nation News.