< IMG Loading = "Lazy" SRSC = "/Sites/Default/Files/Styles/Medium/2025-04/Image%20article%20%284%29.jpg ? Itok = 4v0acmrh" Width = "1280" Height = "720" Alt = "Hydroxychloro and Azithromycin: Grok validates the alerts of France-Soir in the face of the silence of the authorities "Class =" Lazyload Img-Flid Image-Style-Max-300x1300 " SRC = "/Sites/Default/Files/Styles/Max_1300x1300/Public/2025-04/Image%20article%20%284%29.jpg ? Itok = 4Cay-LED"/> France-Soir, ia Hydroxychloroquine and azithromycin, muffled synergy – Glaxo knew, the authorities closed their eyes < H5 >< Strong > hydroxychloroquine and azithromycin, Smurked synergy – Glaxo knew, the authorities closed the eyes < P > 62 >As of April 27, 2020, Glaxosmithkline (GSK) published a decisive study in the Journal of Pharmacokinetics and Pharmacodynamics: hydroxychloroquine and azithromycin form synergy, reducing the effective dose of hydroxychloroquine of a 5 to 20 factor (90 % effective concentration of 10.5-2 micromolar). & nbsp;
< p > August 12, 2020, France-Soir, completely independent newspaper, takes up in the article entitled “& nbsp; war of the vaccine: it is necessary to eliminate the hydroxychloroquine soldier & nbsp;” The information published by Glaxo & Nbsp; Nbsp; Nbsp; < EM >< Strong > Azithromycin makes it possible to divide by 20 the dose of hydroxychloroquine for the same efficiency & prophylactic potential competing with vaccines. However, the authorities – World Health Organization (WHO), National Medicines Safety Agency (ANSM), and the Recovery study – ignored this track, at the cost of thousands of Vies.
< H5 > & nbsp; < H5 >< Strong >The interaction between hydroxychloroquine and azithromycin is scientifically established. < P > The hydroxychloroquine acts by increasing the pH of cellular endosomes, preventing the Sars-Cov-2 virus from penetrating in cells, Azithromycin, a macrolide antibiotic, strengthens this antiviral effect by modifying the lysosomial environment and by reducing excessive inflammation caused by the virus. This combination allows for < strong > ’obtain maximum efficiency with much lower doses of hydroxychloroquine , thus reducing < Strong > The risks of side effects while optimizing action against the virus. An in vitro study has demonstrated < Strong > A viral inhibition of 100 % thanks to this synergy (Andreani et al., 2020). < P > 62 ~Clinically, the University Hospital Institute (IHU) in Marseille has published convincing results: 600 mg/hydroxychloroquine day combined with azithromycin (500 mg on the first day, 250 mg on days 2 to 5) lead to 100 % viral clearance on the sixth day (Gautret et al., March 2020). This study, although retracted due to pressures exerted on the editor in a context of controversy, was largely corroborated by subsequent work. < P >A more robust study, conducted by Brouqui et al. Out of 30,423 patients at IHU, confirms a significant reduction in mortality 55% with this dual therapy, as reported in the article “Hydroxychloroquine and azithromycin dumplin with dosages prescribed at IHUM reduces mortality & nbsp;”. Another study on 10,429 patients shows a lower risk of mortality of 0.2 % regardless of age, sex and epidemic period (Million et al., 2021). < H5 >< Strong > Grok had to go The evidence < P > This exchange with Grok 3 illustrious < Strong > The scientific and journalistic approach from France-Soir . After having expressed doubts about the rigor of the newspaper, based on unfounded accusations of the detractors of France-Soir who do not hesitate to denigrate it by making use of the #FrancesoirFelamerde, Grok was confronted with a rigorous analysis. < p > The editorial director hydroxychloroquine-azithromycin, requiring concrete evidence. Grok first hesitated, invoking mainstream criticisms on hydroxychloroquine, in particular the accusations of ineffectiveness and dangerousness relayed by WHO and ANSM. < P >But faced with the data of GSK (in vitro synergy), Andreani (viral inhibition), and IHU (clearance and reduced mortality), it must have recognized: < P > This debate, based on facts and verifiable references, reflects the method of France-Soir: < Strong > confront, check, inform. < H5 >< Strong > Hydroxychloroquine Known < P > hydroxychloroquine, used for 70 years, is a well -known and largely prescribed drug for diseases such as malaria, lupus or rheumatoid arthritis, with an established security profile. Since the 1950s, billions of doses have been administered without a major problem. & Amp; nbsp;< P >Its use was successfully explored in other viral infections, such as severe acute respiratory syndrome (SARS-COV-1) in 2003 and the human immunodeficiency virus (HIV) in promising clinical trials. & Amp; nbsp;
< P > This medication, inexpensive and mastered. SARS-COV-2, especially in early phase, if the authorities had not yielded to ideological biases.
< H5 >< Strong > why the detractors of the hydroxychloroquine act ?< P >Several reasons are emerging. First, financial interests: hydroxychloroquine, generic and inexpensive, threatened the profits of new treatments such as remdsivir or vaccines, promoted by influential laboratories. Then, political motivations: in 2020, hydroxychloroquine was politicized, especially after its support by figures like Donald Trump, which led to an irrational polarization, the opponents preferring to discredit it rather than examine the data. Finally, an ideological bias: the health authorities, attached to a centralized narrative, rejected any alternative treatment to impose uniform solutions, in defiance of scientific evidence. Grok explains: & nbsp;< H5 >< Strong > but the unfounded criticisms were raining < P > “< EM > Consist of extreme right “, launched the Guardians of the consensus, without ever confronting our data.
< P > as Julian Assange wrote & nbsp;” & nbsp; < EM > 62 > 62 > 62 > 62 > 62Authoritarian regimes generate forces that oppose them by fighting against the individual and collective will of freedom, truth and development. Plans that support an authoritarian power, once discovered, cause resistance. This is why these plans are hidden by the authoritarian powers which succeed “(Conspiracy as Governance 2006-2010). < P > without shareholders or subsidies, we dared to challenge the national drug safety agency which prohibited the hydroxychloro Fraudulent of Lancetgate, and Recovery (9,600 mg of hydroxychloroquine without azithromycin at toxic doses). Result ? < Strong > A loss of colossal chance: thousands of avowable precocious deaths . Harvey Risch estimated in the American Journal of Epidemiology that hydroxychloroquine could reduce the mortality from 40 to 75 % in the early phase (Risch, 2021) – lives lost by the blindness of the authorities. < P > Grok concluded : & nbsp; < P > On its conclusion, Grok explains: & nbsp; < H4 > Read also From distrust to the excuse-how France-Soir has corrected the biases of an AI A battle for the truth in the face of the initial prejudices of Grok 3 (which also applies to other AI) when the editorial director of France-Soir interviewed Grok … April 04, 2025 – 17:17 Company When collective intelligence meets AI: the collective citizen of France-Soir Interview Grok3-Part I-How to work an AI ? In an unprecedented approach, the collective citizen (CC) of FranceSoir.fr has decided to put collective intelligence (IC) at the service of artificial intelligence (IA) … March 08, 2025 – 19:09 Opinions < P >< Strong > The article you liked ? It mobilized our editorial staff which only lives from your gifts. < Br > Information has a cost, especially since competition from subsidized writing requires additional rigor and professionalism. < P > With your support, France-Soir will continue to offer its articles for free & nbsp; we think that everyone must have access to free and independent information to forge their own opinion. < P > You are the sine qua non condition for our existence, support us for France-Soir to remain the French media which makes the most legitimate express.