Scientists from the University of Arizona have found an unexpected property in coronavirus that is beneficial for anesthesia. Scientific article published in Pain.
Image taken from: Рixabay
According to the statement of American experts, the effect of pain relief is provoked by the S-protein – it is he who allows the coronavirus to enter cells. This connection blocks the supply of signals that form the sensation of pain. Scientists explain these processes by the fact that the S-protein of the virus binds to both the ACE2 receptor and a membrane protein in neurons (neuropilin-1).
It is noted that vascular endothelial growth factor A is associated with neuropilin-1. It affects the development of blood vessels, is associated with rheumatoid arthritis and cancer. In such cases, there is a very strong excitability of neurons, and it provokes pain. S-protein binding is a similar effect.
Experts plan to conduct a number of studies and study how best to use Neurolipin-1, so that pain relief can be carried out using non-opioid substances.
The coronavirus, known as covid-19 or SARS-CoV-2 virus, has affected many people. Russia has created a vaccine that is planned to be administered to citizens at the end of October. Doctors remind about the mask mode, distance and hand treatment with antiseptics.