Antibiotic helped the immune system to identify cells with HIV

Antibiotic helped the immune system to identify cells with HIV

Scientists have found a way to help the immune system identify cells with HIV. To do this, they suggest using a special antibiotic that has an effect on the disease.

Antibiotic helped the immune system to identify cells with HIV

Scientists have been studying HIV for many years, trying to find a cure for it. The mechanism of the effect of the disease on the body and how it deceives the immune system is already known, remaining unnoticed. To see cellular abnormalities, the immune system needs to use the major histocompatibility complex proteins. These are very important molecules that are found in almost all cell groups. Thanks to these particles, the proteins that detect viruses are fixed, but HIV contains the Nef protein. It blocks the synthesis of detecting disorders, since the infected molecules are not exposed to the surface of the cell membrane. In that case, the immune system cannot detect HIV, since it blinds it, depriving it of important markers. Nevertheless, the staff of the University of Michigan managed to find a drug that disables the defense mechanism of the disease. By itself, it has no effect on it, but it makes it possible for the body to identify a disease.

We are talking about antibiotics from the macrolide group. They are toxic and can negatively affect the body, but one of them, concanamycin A, is less dangerous. It is possible to develop a dosage that will not affect the cells, but at the same time will already be able to show HIV immunity. Experiments have already been conducted that have shown good results, but researchers will be able to learn more only after the start of clinical trials.

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