Specialists representing the Methodist Hospital in Houston have identified the most dangerous Covid-19 D614G mutation, which increases the increase in its viral load. However, American scientists did not find a connection between the number of particles of infection in the human body and the severity of the disease caused by it.
The study, which began in March, examined over 5,000 samples of the Covid-19 strain. As it turned out, until this time in Houston, the new coronavirus spread in waves: one was observed in the spring, and the second in the summer. It was among citizens who became infected in a later period that a dangerous mutation was identified, which received the designation D614G. It is dangerous by the increase in the number of “spikes” on the virus. These “build-ups” allow the infection to cling to cells, increasing its ability to infect them.
When infected with this form, a larger number of virus particles enter the body, which increases the load, and this, in turn, leads to an increase in the rate of its spread. However, the severity of the course of the disease is not related to the number of harmful molecules, writes medRxiv.
Earlier, Rospotrebnadzor announced the detection of 22 single mutations of Covid-19, of which the D614G and P314L species are the most common. In the countries of Western Europe, as the study shows, it was these variants of the new coronavirus strains that circulated, and in the spring they were brought to Russia.